The Human Pangenome Project (HPP), initiated in 2020, is a global endeavor aimed at creating a comprehensive and inclusive reference of human genetic diversity. The project is designed to move beyond the traditional single-reference concept to a pangenome that encompasses the full spectrum of human genetic variation. By including genome sequences from diverse populations across the globe, the HPP seeks to represent the genetic diversity of the human species more accurately. The Human Pangenome dataset includes high-quality genome sequences from individuals around the world, with an emphasis on underrepresented populations to fill the gaps in our current genetic knowledge. By doing so, it aims to facilitate more inclusive and precise genetic research, improving our understanding of human biology and aiding in the development of more effective personalized medicine. The dataset encompasses the latest release of the Human Pangenome, featuring comprehensive annotations of genetic variants, structural variations, and an array of functional data. The project has put a particular focus on ensuring the privacy and ethical considerations of participants, adopting rigorous standards to...
This collection is openly accessible.
Human Pangenome Reference is published on Biomedical AI.